Isabella was born in Madrigal de las Altas Torres, Ávila, to John II of Castile and Isabella of Portugal on 22 April 1451.[1] At the time of her birth, her older half-brother Henry preceded her in the line of succession. Henry was 26 at that time and married, but childless. Her younger brother Alfonso was born two years later on 17 November 1453 and displaced her in the line of succession.[2] When her father died in 1454, her half-brother ascended the throne as Henry IV. Isabella and Alfonso were left in Henry's care.[3] Her brother Alfonso, mother, and she then moved to Arévalo.[4]
These were times of turmoil for Isabella. She lived with her brother and her mother in a castle in Arevalo under poor conditions, where they suffered from a shortage of money. Although her father arranged in his will for his children to be financially well taken care of, her half-brother Henry did not comply with their father's wishes, either from a desire to keep his half-siblings restricted or from ineptitude.[3] Even though the living conditions were lackluster, under the careful eye of her mother, Isabella was instructed in lessons of practical piety and in the deep reverence for religion.
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